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DNA Genetic Screening

Genetic testing uses genomics technologies laboratory methods to look at your genes, which are the DNA instruction; you inherit from your parents. Genetic tests may be used to identify increased risks of health problems, to choose treatments, or to assess responses to treatments. These markers are associated with disease or disorders such as cardiovascular disease, metabolic disorders, cancers and even developmental disorders.

Beyond disease, genetic screening is also able to identity traits that may affect health, wellness and fitness. These include traits that are associated with metabolism of nutrients, anti-aging, cellular detoxification, anti-oxidative capacity, diet and weight management. In addition, genetic markers may also indicate your risks for adverse reactions towards certain types of medications. In addition, genetic markers may also indicate your risks for adverse reactions towards certain types of medications.

 

What are the benefits of DNA Genetic Screening?

Have potential benefits whether the results are positive or negative for a gene mutation. Test results can provide a sense of relief from uncertainty and help people make informed decisions about managing their health care. For example, a negative result can eliminate the need for unnecessary checkups and screening tests in some cases. A positive result can direct a person toward available prevention, monitoring, and treatment options. Some test results can also help people make decisions about having children. Newborn screening can identify genetic disorders early in life so treatment can be started as early as possible.

 

Genetic Screening For :

  • Wellness
 & Fitness
  • Cancers
  • Metabolic Disorders
  • Cardiovascular Diseases
  • Children
  • PGx

This screens 154 genes in the DNA & 240 genetics markers to identify a person’s current well being.

Wellness Screens For Genetic Markers That Are Associated With:
  • reresponse towards nutrition and dietary supplements
  • metabolism of nutrients
  • weight management
  • cellular detoxification
  • antioxidant capacity
  • response to exercise
  • susceptibility towards injuries related to physical activities.
Diet And Nutrient Management
  • Eye health : Carotene and vitamin A metabolism
  • Heart Health : Homocysteine metabolism, salt sensitivity high blood pressure and inflammatory response
  • Metabolic Health : Insulin resistance, metabolic syndrome, carbohydrate metabolism and inflammatory response
  • Antioxidative ability : Vitamin C, vitamin E, selenium and coenzyme Q10
  • Liver function : Detoxification phase 1 and 2, and steroid metabolism
  • Vitality : Vitamin B6, vitamin B12 and coenzyme Q10
  • Dietary Sensitives : Caffeine metabolism, lactose intolerance, and omega 3 and 6 balance.
Mental And Physical Performance
  • Fitness : Power, endurance and exercise intensity
  • Stamina : Oxygen uptake and utilisation
  • Muscle Performance : Energy utilisation
  • Weight Management : Lipid metabolism and obesity
  • Mental Health : Stress sensitivity
  • Physiological Response : Pain sensitivity and inflammatory response
Prevention Of Injuries
  • Bone Health : Osteoporotic fracture, vitamin D and calcium metabolism
  • Connective Tissue Health : Tendon and ligament injuries and collagen metabolism
  • Age-Related Joint Health : Osteoarthritis
  • Sports-Induced Risks : Sudden cardiac arrest , Head injury: concussion , Soft tissue and exercise-induced muscle injury

Cancer screening is the test screens your DNA for markers that are linked ato inherited risk factors for cancers. The markers serves as “red Flag” in your DNA and can indicate if you are predisposed to certain type of cancer.

Cancer refers to the uncontrollable division and growth of cells in the human body. The growth, or tumour, originates from mutations in a person’s DNA. These mutations can also be passed down from parent to child, or may be prevalent among siblings.

Cancer can develop in any part of the human body but those associated with the breast, colon and lung are more common in Malaysia.

Benefits of Genetic Screening for Cancers

This screening is relevant for individuals with a family. History of cancer, and for those who carry increased health risks associated with environmental or behavioural factors. If detected early, a cancer may be better controlled with medical advice and treatment.

An individual already diagnosed with cancer may want his or her family members to undergo this Onco test. This can give a more comprehensive picture of the prevalence of cancer markers within a family. Hence, family members can be better informed of their predisposition towards the cancer, and take the necessary steps to maintain their health.

Cancer screens your DNA for genetic markers associated with 31 cancers that include:
  • Bladder Cancer
  • Blood Cancer (Leukaemia and Lymphoma)
  • Breast Cancer
  • Cervical Cancer
  • Colorectal Cancer
  • Liver Cancer
  • Lung Cancer
  • Nasopharyngeal Cancer
  • Ovarian Cancer
  • Pancreatic Cancer
  • Prostate Cancer
  • Renal Cancer

Oncology screens your DNA for inherited risk of cancers. With the information from these markers, you can be better prepared to make lifestyle and dietary changes to mitigate your health risks, if necessary.


Metabolic is especially relevant for high risk individuals with a family history of metabolic disease, and for those who carry increased health risks associated with the environmental or behavioural factors.

Metabolic genetic screening is designed to screen for genetic markers that are linked to metabolic disease. These markers include those that are relevant to the Asian population.

Metabolic disorders affect the body’s ability to properly convert food into energy. These disorder can lead to other serious or even fatal illness, such as cardiovascular diseases and cancers.

It is important to understand your genetic risk factors for common metabolic disorders. If detected early, these diseases may be better controlled with appropriate changes to your lifestyle, and with timely medical advice and treatment.

There are many types of metabolic disease, which include G6PD deficiency, lactose intolerance, thyroid problems and gallstone disease. The two most common metabolic disorders are highlighted below.

Metabolic screens your DNA for genetic markers associated with the following metabolic disorders:

Chronic Thyroiditis
  • Diabetes Type 1
  • Diabetes Type 2
Gallstone Disease
  • Gestational Diabetes (Diabetes in pregnancy)
  • Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
  • Gout
  • Grave’s Disease (exercise production of throid hormones)
  • Hypercholesterolemia (higher than normal cholestrol levels)
  • Hypertriglyceridemia
  • Hypothyrodism
  • Lactose Intolerance
  • Metabolic Syndrome (increase risk of heart disease, stroke and diabetes)

Cardio identifies genetic risks of developing cardiovascular diseases by screening for genetic markers. These genetic markers are medically-linked with an increased risk of developing cardiovascular diseases (CVD). By having better knowledge of some of your genetic risks for CVD, you will be in a position to make positive changes to your lifestyle and diet, if necessary.

Cardiovascular disease affects the heart and the circulatory system. In 2008, CVD such as heart attack, high blood pressure and stroke killed more than 17 million people, and this number is likely to double by 2030.

Cardio screens your DNA for genetic markers associated with the following disease and adverse drug reactions.

Cardiovascular Diseases:
  • Aneurysm (dilation of blood vessel wall)
  • Atrial Fibrillation (irregular rapid heart beat)
  • Coronary Heart Disease (blockage of the arteries to the heart)
  • Deep Vein Thrombosis (blood clot in deep vein)
  • Pulmonary Embolism (sudden blockage in lung artery)
  • Familial hypercholesterolemia (disorder that causes high cholesterol levels)
  • Hypertension (high blood pressure)
  • Hypertriglyceridemia (high blood triglycerides)
  • Myocardial Infarction (heart attack)
  • Obesity
  • Peripheral Arterial Disease
  • Stroke
  • Sudden Cardiac Arrest
  • Chronic Obstructive Pulmonary Disease (obstruction of bronchial air flow)

The earlyyears of a child’s life are among the most precious for parents. It is important to detect teg risks of any illness or conditions which may hinder or drastically impact the physical and mental development of a child as early as possible.

This test screens your child’s DNA for genetic markers across a wide range of genes that are linked to inherited illness or conditions. These markers serve as ‘red flags’ in the DNA and can indicate if your child is predisposed towards immunological disease, developmental disorders or other health conditions.

With this child screening you can be better prepared to manage your child’s health, if necessary. It uses the latest research technologies available from Life Technologies Corporation, USA. This test also includes a number of markers that have been associated with learning disabilities, neurological conditions, and developmental and lifestyle-related disorders.

Benefits of Children Genetic DNA Screening

Child genetic screening enables you to have a clearer understanding of your child’s health. For parents with children who are suffering from an unidentified inherited illness or condition, This Children Genetic Screening may help prevent years of unnecessary testing and worrying about the unknown.

Child screens your child’s DNA for the following illness or conditions:
  • Abnormal QT Interval
  • Adolescent Idiopathic Scoliosis
  • Allergic Rhinitis
  • Asthma
  • Atopic Dermatitis
  • Attention Deficit Hyperactivity Disorder
  • Coeliac Disease
  • Crohn’s Disease
  • Dyslexia
  • Early or Late Teething
  • Epilepsy
  • Infantile Hypertrophic Pyloric Stenosis

The study of human genetic variance that influences an individual’s response to drug therapy, in particular, the risk for an Adverse Drug Reaction (ADR). One in four patients are prescribed drugs which could injure them. This screens your DNA for clinically relevant genetic markers which are associated with drug response and adverse drug reaction risks. The test results can identify appropriate medication and suitable drug dosages based on your personal genetic profile.

  • Invasive Pneumococcal Disease
  • Juvenile Idiopathic Arthritis
  • Kawasaki’s Disease
  • Lactose Intolerance
  • Meningococcal Disease
  • Obesity
  • Obsessive Compulsive Disorder
  • Pathological Myopia
  • Permanent Tooth Development
  • Restless Legs Syndrome
  • Tourette Syndrome
  • Ulcerative Colitis

 

FAQ - DNA Genetic Screening

  • IS DNA Genetic Screening Safe?

    Genetic screening is absolutely safe. Samples are collected using a buccal swab, which involve rubbing a swab against the inner side of the check. A blood sample can also be used for the screening.

  • Do I have to repeat the test?

    Each type of genetic screening test only has to be taken once in your lifetime.

  • How soon can I get my results?

    Depending on the type of tests requested, genetic screening and analysis in the laboratory generally take about 10-20 working days from sample collection to receipt of results.

  • What is the difference between a normal blood test and genetic screening?

    A normal blood test detects changes in your body when a disease is already present. Generic Screeening detects risks for a disease even before the onset of that particular diseases. It is best to take both type of tests together to get a more complete picture of your health risks.

  • How accurate of Genetic Screening?

    All tests are accurate for known genetic markers. Complex diseases may require comprehensive tests that utilize a wider range of markers, or DNA sequencing. Our Doctor can advice on the necessity for such tests. It is still important to validate the results from genetic screening with medical tests.

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